Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK017806-21
Application #
2137132
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1975-01-01
Project End
1999-11-30
Budget Start
1996-02-01
Budget End
1996-11-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Hawaii
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
121911077
City
Honolulu
State
HI
Country
United States
Zip Code
96822
Liu, Robert S H; Colmenares, Leticia U (2003) The molecular basis for the high photosensitivity of rhodopsin. Proc Natl Acad Sci U S A 100:14639-44
Liu, Robert S H (2002) Introduction to the symposium-in-print: photoisomerization pathways, torsional relaxation and the hula twists. Photochem Photobiol 76:580-3
Liu, R S; Hammond, G S (2001) Examples of hula-twist in photochemical cis- trans isomerization. Chemistry 7:4537-44
Liu, R S (2001) Photoisomerization by hula-twist: a fundamental supramolecular photochemical reaction. Acc Chem Res 34:555-62
Muthyala, R; Watanabe, D; Asato, A E et al. (2001) The nature of the delocalized cations in azulenic bacteriorhodopsin analogs. Photochem Photobiol 74:837-45
Liu, R S; Hammond, G S (2000) The case of medium-dependent dual mechanisms for photoisomerization: one-bond-flip and hula-twist. Proc Natl Acad Sci U S A 97:11153-8
Imai, H; Hirano, T; Terakita, A et al. (1999) Probing for the threshold energy for visual transduction: red-shifted visual pigment analogs from 3-methoxy-3-dehydroretinal and related compounds. Photochem Photobiol 70:111-5
Li, X Y; Liu, R S (1995) Photostationary state compositions of retinal and related compounds included in beta-lactoglobulin. Effects of protein host on isomer distribution of polyene substrates. Photochem Photobiol 62:361-6
Asato, A E; Peng, A; Hossain, M Z et al. (1993) Azulenic retinoids: novel nonbenzenoid aromatic retinoids with anticancer activity. J Med Chem 36:3137-47
Liu, R S; Krogh, E; Li, X Y et al. (1993) Analyzing the red-shift characteristics of azulenic, naphthyl, other ring-fused and retinyl pigment analogs of bacteriorhodopsin. Photochem Photobiol 58:701-5

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