Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK018532-12S1
Application #
3226072
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1978-05-01
Project End
1987-06-30
Budget Start
1987-05-01
Budget End
1987-06-30
Support Year
12
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Rockefeller University
Department
Type
Graduate Schools
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Freedman, S D; Kern, H F; Scheele, G A (1998) Cleavage of GPI-anchored proteins from the plasma membrane activates apical endocytosis in pancreatic acinar cells. Eur J Cell Biol 75:163-73
Freedman, S D; Kern, H F; Scheele, G A (1998) Acinar lumen pH regulates endocytosis, but not exocytosis, at the apical plasma membrane of pancreatic acinar cells. Eur J Cell Biol 75:153-62
Freedman, S D; Scheele, G A (1993) Reversible pH-induced homophilic binding of GP2, a glycosyl-phosphatidylinositol-anchored protein in pancreatic zymogen granule membranes. Eur J Cell Biol 61:229-38
Fukuoka, S; Zhang, D E; Taniguchi, Y et al. (1993) Structure of the canine pancreatic colipase gene includes two protein-binding sites in the promoter region. J Biol Chem 268:11312-20
Fukuoka, S; Freedman, S D; Yu, H et al. (1992) GP-2/THP gene family encodes self-binding glycosylphosphatidylinositol-anchored proteins in apical secretory compartments of pancreas and kidney. Proc Natl Acad Sci U S A 89:1189-93
Fukuoka, S; Scheele, G A (1991) Novel strategy for synthesis of full-length double-stranded cDNA transcripts without dC-dG tails. Nucleic Acids Res 19:6961-2
Leach, S D; Modlin, I M; Scheele, G A et al. (1991) Intracellular activation of digestive zymogens in rat pancreatic acini. Stimulation by high doses of cholecystokinin. J Clin Invest 87:362-6
Fukuoka, S; Freedman, S D; Scheele, G A (1991) A single gene encodes membrane-bound and free forms of GP-2, the major glycoprotein in pancreatic secretory (zymogen) granule membranes. Proc Natl Acad Sci U S A 88:2898-902