Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK019318-20
Application #
2137305
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1994-09-12
Project End
1998-06-30
Budget Start
1996-08-22
Budget End
1997-06-30
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Tang, Guanghua; Wang, Ying; Park, Sangeun et al. (2012) Go2 G protein mediates galanin inhibitory effects on insulin release from pancreatic ? cells. Proc Natl Acad Sci U S A 109:2636-41
Pero, Ralph S; Borchers, Michael T; Spicher, Karsten et al. (2007) Galphai2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation. Proc Natl Acad Sci U S A 104:4371-6
Fan, Hongkuan; Williams, David L; Zingarelli, Basilia et al. (2007) Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins. Immunology 122:116-23
Gohla, Antje; Klement, Karinna; Piekorz, Roland P et al. (2007) An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver. Proc Natl Acad Sci U S A 104:3003-8
Fan, Hongkuan; Williams, David L; Zingarelli, Basilia et al. (2006) Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins. Biochim Biophys Acta 1763:1051-8
Wei, Bo; Velazquez, Peter; Turovskaya, Olga et al. (2005) Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets. Proc Natl Acad Sci U S A 102:2010-5
Pineda, Victor V; Athos, Jaime I; Wang, Hongbing et al. (2004) Removal of G(ialpha1) constraints on adenylyl cyclase in the hippocampus enhances LTP and impairs memory formation. Neuron 41:153-63
Foerster, Katharina; Groner, Ferdi; Matthes, Jan et al. (2003) Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors. Proc Natl Acad Sci U S A 100:14475-80
Dhingra, Anuradha; Jiang, Meisheng; Wang, Tian-Li et al. (2002) Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o). J Neurosci 22:4878-84
Jiang, M; Spicher, K; Boulay, G et al. (2001) Most central nervous system D2 dopamine receptors are coupled to their effectors by Go. Proc Natl Acad Sci U S A 98:3577-82

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