Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK019394-19
Application #
2137315
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1976-05-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Nair, Devi M; Purdue, P Edward; Lazarow, Paul B (2004) Pex7p translocates in and out of peroxisomes in Saccharomyces cerevisiae. J Cell Biol 167:599-604
Lazarow, Paul B (2003) Peroxisome biogenesis: advances and conundrums. Curr Opin Cell Biol 15:489-97
Yang, X; Purdue, P E; Lazarow, P B (2001) Eci1p uses a PTS1 to enter peroxisomes: either its own or that of a partner, Dci1p. Eur J Cell Biol 80:126-38
Purdue, P E; Lazarow, P B (2001) Peroxisome biogenesis. Annu Rev Cell Dev Biol 17:701-52
Purdue, P E; Lazarow, P B (2001) Pex18p is constitutively degraded during peroxisome biogenesis. J Biol Chem 276:47684-9
Santos, M J; Henderson, S C; Moser, A B et al. (2000) Peroxisomal ghosts are intracellular structures distinct from lysosomal compartments in Zellweger syndrome: a confocal laser scanning microscopy study. Biol Cell 92:85-94
Purdue, P E; Skoneczny, M; Yang, X et al. (1999) Rhizomelic chondrodysplasia punctata, a peroxisomal biogenesis disorder caused by defects in Pex7p, a peroxisomal protein import receptor: a minireview. Neurochem Res 24:581-6
Purdue, P E; Yang, X; Lazarow, P B (1998) Pex18p and Pex21p, a novel pair of related peroxins essential for peroxisomal targeting by the PTS2 pathway. J Cell Biol 143:1859-69
Purdue, P E; Zhang, J W; Skoneczny, M et al. (1997) Rhizomelic chondrodysplasia punctata is caused by deficiency of human PEX7, a homologue of the yeast PTS2 receptor. Nat Genet 15:381-4
Purdue, P E; Lazarow, P B (1996) Identification of yeast peroxisomal membrane ghosts. Ann N Y Acad Sci 804:660-2

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