Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK021505-13
Application #
3227007
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1978-04-01
Project End
1994-06-30
Budget Start
1990-01-01
Budget End
1990-06-30
Support Year
13
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Giannasca, K T; Giannasca, P J; Neutra, M R (1996) Adherence of Salmonella typhimurium to Caco-2 cells: identification of a glycoconjugate receptor. Infect Immun 64:135-45
Zhou, F; Kraehenbuhl, J P; Neutra, M R (1995) Mucosal IgA response to rectally administered antigen formulated in IgA-coated liposomes. Vaccine 13:637-44
Trahair, J F; Wilson, J M; Neutra, M R (1995) Identification of a marker antigen for the endocytic stage of intestinal development in rat, sheep, and human. J Pediatr Gastroenterol Nutr 21:277-87
Pakkanen, R; Neutra, M (1994) Bovine colostrum ultrafiltrate: an effective supplement for the culture of mouse-mouse hybridoma cells. J Immunol Methods 169:63-71
Giannasca, P J; Giannasca, K T; Falk, P et al. (1994) Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines. Am J Physiol 267:G1108-21
Amerongen, H M; Wilson, G A; Fields, B N et al. (1994) Proteolytic processing of reovirus is required for adherence to intestinal M cells. J Virol 68:8428-32
Neutra, M R; Kraehenbuhl, J P (1994) Mucosal immunization via M cells for production of protective secretory IgA antibodies. Am J Trop Med Hyg 50:10-3
Reinhart, F D; Phillips, T E; Trahair, J F et al. (1994) Identification of R-GRAMP, a membrane glycoprotein of regulated secretory granules in primate cells. Eur J Cell Biol 64:243-56
Michetti, P; Porta, N; Mahan, M J et al. (1994) Monoclonal immunoglobulin A prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium. Gastroenterology 107:915-23
Apter, F M; Lencer, W I; Finkelstein, R A et al. (1993) Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro. Infect Immun 61:5271-8

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