Pancreatic Islet Cell Studies

Rabinovitch, Alexander

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 3R01DK025832-08S1
• Application #: 3227619
• Study Section: Metabolism Study Section (MET)
• Project Start: 1979-09-01
• Project End: 1990-08-31
• Budget Start: 1987-07-01
• Budget End: 1987-08-31
• Support Year: 8
• Fiscal Year: 1987

Institution

• Name: University of Miami School of Medicine
• Type: Schools of Medicine
• City: Miami
• State: FL
• Country: United States
• Zip Code: 33101

Publications

Rabinovitch, A; Baquerizo, H; Sumoski, W (1990) Cytotoxic effects of cytokines on islet beta-cells: evidence for involvement of eicosanoids. Endocrinology 126:67-71

Baquerizo, H; Rabinovitch, A (1990) Interferon-gamma sensitizes rat pancreatic islet cells to lysis by cytokines and cytotoxic cells. J Autoimmun 3 Suppl 1:123-30

Rabinovitch, A; Baquerizo, H; Pukel, C et al. (1989) Effects of cytokines on rat pancreatic islet cell monolayer cultures: distinction between functional and cytotoxic effects on islet beta-cells. Reg Immunol 2:77-82

Banovac, K; Zakarija, M; Rabinovitch, A (1989) A study of hepatic metabolism of thyroxine in BB/W rats treated with L-thyroxine. Horm Metab Res 21:69-72

Banovac, K; Ghandur-Mnaymneh, L; Leone, J et al. (1989) Intrathyroidal mast cells express major histocompatibility complex class-II antigens. Int Arch Allergy Appl Immunol 90:43-6

Baquerizo, H; Leone, J; Pukel, C et al. (1989) Mechanisms of cyclosporine protection against spontaneous diabetes mellitus in the BB/W or rat. J Autoimmun 2:133-50

Banovac, K; Neylan, D; Leone, J et al. (1989) Are the mast cells antigen presenting cells? Immunol Invest 18:901-6

Rabinovitch, A; Pukel, C; Baquerizo, H (1988) Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures. Endocrinology 122:2393-8

Pukel, C; Baquerizo, H; Rabinovitch, A (1988) Destruction of rat islet cell monolayers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin 1. Diabetes 37:133-6

Banovac, K; Ghandur-Mnaymneh, L; Zakarija, M et al. (1988) The effect of thyroxine on spontaneous thyroiditis in BB/W rats. Int Arch Allergy Appl Immunol 87:301-5