Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK027237-10
Application #
3228235
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1979-12-01
Project End
1989-05-31
Budget Start
1988-12-01
Budget End
1989-05-31
Support Year
10
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Type
School of Medicine & Dentistry
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Wu, M L; Morgan, W T (1995) Thermodynamics of heme-induced conformational changes in hemopexin: role of domain-domain interactions. Protein Sci 4:29-34
Faber, H R; Groom, C R; Baker, H M et al. (1995) 1.8 A crystal structure of the C-terminal domain of rabbit serum haemopexin. Structure 3:551-9
Cox, M C; Le Brun, N; Thomson, A J et al. (1995) MCD, EPR and NMR spectroscopic studies of rabbit hemopexin and its heme binding domain. Biochim Biophys Acta 1253:215-23
Wu, M L; Morgan, W T (1994) Conformational analysis of hemopexin by Fourier-transform infrared and circular dichroism spectroscopy. Proteins 20:185-90
Morgan, W T; Muster, P; Tatum, F et al. (1993) Identification of the histidine residues of hemopexin that coordinate with heme-iron and of a receptor-binding region. J Biol Chem 268:6256-62
Baker, H M; Norris, G E; Morgan, W T et al. (1993) Crystallization of the C-terminal domain of rabbit serum hemopexin. J Mol Biol 229:251-2
Wu, M L; Morgan, W T (1993) Characterization of hemopexin and its interaction with heme by differential scanning calorimetry and circular dichroism. Biochemistry 32:7216-22
Muster, P; Tatum, F; Smith, A et al. (1991) Further characterization of structural determinants of rabbit hemopexin function. J Protein Chem 10:123-8
Smith, A; Farooqui, S M; Morgan, W T (1991) The murine haemopexin receptor. Evidence that the haemopexin-binding site resides on a 20 kDa subunit and that receptor recycling is regulated by protein kinase C. Biochem J 276 ( Pt 2):417-25
Tatum, F; Alam, J; Smith, A et al. (1990) Molecular cloning, nucleotide sequence heterozygosity and regulation of rabbit serum amyloid A cDNA. Nucleic Acids Res 18:7447

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