Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK027400-16
Application #
2137992
Study Section
Special Emphasis Panel (ZRG2-CBY-2 (01))
Project Start
1980-12-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Texas Health Science Center Houston
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225

  Publications

Loflin, Paul; Lever, Julia E (2002) Cyclic nucleotide-dependent screening of a lamda expression library for nucleic acid binding activities. Biotechniques 32:1020, 1022, 1024-5 passim
Loflin, P; Lever, J E (2001) A cis-dominant cyclic nucleotide-dependent regulatory domain in the 3'-untranslated region of Na(+)/glucose cotransporter (SGLT1) mRNA. FEBS Lett 492:233-7
Loflin, P; Lever, J E (2001) HuR binds a cyclic nucleotide-dependent, stabilizing domain in the 3' untranslated region of Na(+)/glucose cotransporter (SGLT1) mRNA. FEBS Lett 509:267-71
Lee, W Y; Loflin, P; Clancey, C J et al. (2000) Cyclic nucleotide regulation of Na+/glucose cotransporter (SGLT1) mRNA stability. Interaction of a nucleocytoplasmic protein with a regulatory domain in the 3'-untranslated region critical for stabilization. J Biol Chem 275:33998-4008
Clancey, C J; Lever, J E (2000) Differential regulation of three glucose transporter genes in a renal epithelial cell line. J Cell Physiol 185:244-52
Panayotova-Heiermann, M; Loo, D D; Kong, C T et al. (1996) Sugar binding to Na+/glucose cotransporters is determined by the carboxyl-terminal half of the protein. J Biol Chem 271:10029-34
Peng, H; Lever, J E (1995) Regulation of Na(+)-coupled glucose transport in LLC-PK1 cells. Message stabilization induced by cyclic AMP elevation is accompanied by binding of a M(r) = 48,000 protein to a uridine-rich domain in the 3'-untranslated region. J Biol Chem 270:23996-4003
Peng, H; Lever, J E (1995) Post-transcriptional regulation of Na+/glucose cotransporter (SGTL1) gene expression in LLC-PK1 cells. Increased message stability after cyclic AMP elevation or differentiation inducer treatment. J Biol Chem 270:20536-42
Wu, J S; Lever, J E (1994) N-linked glycosylation is not required for Na+/glucose symport activity in LLC-PK1 cells. Biochim Biophys Acta 1192:289-92
Mackenzie, B; Panayotova-Heiermann, M; Loo, D D et al. (1994) SAAT1 is a low affinity Na+/glucose cotransporter and not an amino acid transporter. A reinterpretation. J Biol Chem 269:22488-91

Showing the most recent 10 out of 15 publications