Biochemical Defects in Porphyria

Pimstone, Neville R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK030094-05
• Application #: 3229258
• Study Section: General Medicine A Subcommittee 2 (GMA)
• Project Start: 1981-08-01
• Project End: 1988-11-30
• Budget Start: 1986-12-01
• Budget End: 1987-11-30
• Support Year: 5
• Fiscal Year: 1987

Institution

• Name: University of California Davis
• Type: Schools of Medicine
• DUNS #: 094878337
• City: Davis
• State: CA
• Country: United States
• Zip Code: 95618

Publications

Mukerji, S K; Pimstone, N R (1992) Uroporphyrinogen decarboxylases from human erythrocytes: purification, complete separation and partial characterization of two isoenzymes. Int J Biochem 24:105-19

Mukerji, S K; Pimstone, N R (1990) Free radical mechanism of oxidation of uroporphyrinogen in the presence of ferrous iron. Arch Biochem Biophys 281:177-84

Mukerji, S K; Pimstone, N R (1988) Defective human erythrocyte uroporphyrinogen decarboxylase in familial porphyria cutanea tarda: the metabolic lesion or the result of endogenous porphyrinemia? Biochem Biophys Res Commun 154:39-46

Pimstone, N R; Gandhi, S N; Mukerji, S K (1987) Therapeutic efficacy of oral charcoal in congenital erythropoietic porphyria. N Engl J Med 316:390-3

Mukerji, S K; Pimstone, N R (1987) Evidence for two uroporphyrinogen decarboxylase isoenzymes in human erythrocytes. Biochem Biophys Res Commun 146:1196-203