Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK031391-04A1
Application #
3230032
Study Section
Endocrinology Study Section (END)
Project Start
1983-08-01
Project End
1990-04-30
Budget Start
1987-05-01
Budget End
1988-04-30
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33101
de Forteza, R; Smith, C U; Amin, J et al. (1994) Visualization of the thyrotropin receptor on the cell surface by potent autoantibodies. J Clin Endocrinol Metab 78:1271-3
Wu, Z; Podack, E R; McKenzie, J M et al. (1994) Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease. Clin Exp Immunol 98:470-7
Zakarija, M; De Forteza, R; McKenzie, J M et al. (1994) Characteristics and clinical correlates of a novel thyroid-stimulating autoantibody. Autoimmunity 19:31-7
Levis, S; Ghandur-Mnaymneh, L; McKenzie, J M et al. (1992) Evaluation of the biological significance of leukocyte infiltration of the thyroid in Graves' disease. Int Arch Allergy Immunol 99:37-43
McKenzie, J M; Zakarija, M (1992) Fetal and neonatal hyperthyroidism and hypothyroidism due to maternal TSH receptor antibodies. Thyroid 2:155-9
Peter, H J; Gerber, H; Studer, H et al. (1991) Comparison of FRTL-5 cell growth in vitro with that of xenotransplanted cells and the thyroid of the recipient mouse. Endocrinology 128:211-9
Stein, S A; Zakarija, M; McKenzie, J M et al. (1991) The site of the molecular defect in the thyroid gland of the hyt/hyt mouse: abnormalities in the TSH receptor-G protein complex. Thyroid 1:257-66
Zakarija, M; McKenzie, J M (1991) Autoantibodies to the TSH receptor. Exp Clin Endocrinol 97:165-9
Zakarija, M; McKenzie, J M; Eidson, M S (1990) Transient neonatal hypothyroidism: characterization of maternal antibodies to the thyrotropin receptor. J Clin Endocrinol Metab 70:1239-46
Zakarija, M; McKenzie, J M (1990) Do thyroid growth-promoting immunoglobulins exist? J Clin Endocrinol Metab 70:308-10

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