Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK031722-10
Application #
2138676
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1983-12-01
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Chatterjee, Subroto; Alsaeedi, Nezar (2012) Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models. Adv Exp Med Biol 749:153-69
Chatterjee, Subroto; Pandey, Ambarish (2008) The Yin and Yang of lactosylceramide metabolism: implications in cell function. Biochim Biophys Acta 1780:370-82
Chatterjee, Subroto; Neill, Roger; Shupp, Jeffrey W et al. (2007) Identification of staphylococcal enterotoxin B domains involved in binding to cultured human kidney proximal tubular cells: imparting proliferation and death. Exp Biol Med (Maywood) 232:1142-51
Martin, Sergio F; Williams, Niesha; Chatterjee, Subroto (2006) Lactosylceramide is required in apoptosis induced by N-Smase. Glycoconj J 23:147-57
Chatterjee, Subroto; Berliner, Judith A; Subbanagounder, Ganesamoorthy G et al. (2004) Identification of a biologically active component in minimally oxidized low density lipoprotein (MM-LDL) responsible for aortic smooth muscle cell proliferation. Glycoconj J 20:331-8
Yeh, L H; Kinsey, A M; Chatterjee, S et al. (2001) Lactosylceramide mediates shear-induced endothelial superoxide production and intercellular adhesion molecule-1 expression. J Vasc Res 38:551-9
Chatterjee, S (2000) Assay of lactosylceramide synthase and comments on its potential role in signal transduction. Methods Enzymol 311:73-81
Jan, J T; Chatterjee, S; Griffin, D E (2000) Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide. J Virol 74:6425-32
Chatterjee, S; Han, H; Rollins, S et al. (1999) Molecular cloning, characterization, and expression of a novel human neutral sphingomyelinase. J Biol Chem 274:37407-12
Chatterjee, S (1999) Neutral sphingomyelinase: past, present and future. Chem Phys Lipids 102:79-96

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