Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK035912-03
Application #
3234192
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1987-11-01
Project End
1989-07-31
Budget Start
1987-11-01
Budget End
1988-07-31
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Nicke, B; Tseng, M J; Fenrich, M et al. (1999) Adenovirus-mediated gene transfer of RasN17 inhibits specific CCK actions on pancreatic acinar cells. Am J Physiol 276:G499-506
Detjen, K; Fenrich, M C; Logsdon, C D (1997) Transfected cholecystokinin receptors mediate growth inhibitory effects on human pancreatic cancer cell lines. Gastroenterology 112:952-9
Dabrowski, A; Detjen, K M; Logsdon, C D et al. (1997) Stimulation of both CCK-A and CCK-B receptors activates MAP kinases in AR42J and receptor-transfected CHO cells. Digestion 58:361-7
Detjen, K; Yule, D; Tseng, M J et al. (1997) CCK-B receptors produce similar signals but have opposite growth effects in CHO and Swiss 3T3 cells. Am J Physiol 273:C1449-57
Grady, T; Dabrowski, A; Williams, J A et al. (1996) Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. Biochem Biophys Res Commun 227:1-7
Dabrowski, A; Grady, T; Logsdon, C D et al. (1996) Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 271:5686-90
Simeone, D M; Yule, D I; Logsdon, C D et al. (1995) Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells. Regul Pept 55:197-206
Detjen, K; Yang, J; Logsdon, C D (1995) Muscarinic acetylcholine receptor down-regulation limits the extent of inhibition of cell cycle progression in Chinese hamster ovary cells. Proc Natl Acad Sci U S A 92:10929-33
Detjen, K; Tseng, M J; Logsdon, C D (1995) High- and low-affinity CCKA receptor states mediate specific growth inhibitory effects on CHO cells. Biochem Biophys Res Commun 213:44-51
Hoshi, H; Logsdon, C D (1993) Direct trophic effects of fibroblast growth factors on rat pancreatic acinar cells in vitro. Biochem Biophys Res Commun 196:1202-7

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