Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK036199-10
Application #
2139753
Study Section
Special Emphasis Panel (ZRG7-SSS-5 (02))
Project Start
1985-01-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Texas Tech University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
609980727
City
Lubbock
State
TX
Country
United States
Zip Code
79430
Hayward, A L; Hinojos, C A; Nurowska, B et al. (1999) Altered sodium pump alpha and gamma subunit gene expression in nephron segments from hypertensive rats. J Hypertens 17:1081-7
Eiam-Ong, S; Sabatini, S (1999) Age-related changes in renal function, membrane protein metabolism, and Na,K-ATPase activity and abundance in hypokalemic F344 x BNF(1) rats. Gerontology 45:254-64
Sabatini, S (1999) Experimental studies in distal urinary acidification: bringing the bedside to the bench. Semin Nephrol 19:188-94
Nguyen, A T; Hayward-Lester, A; Sabatini, S et al. (1998) Renal Na+, K+-ATPase in SHR: studies of activity and gene expression. Clin Exp Hypertens 20:641-56
Wesson, D E (1998) Na/H exchange and H-K ATPase increase distal tubule acidification in chronic alkalosis. Kidney Int 53:945-51
Wesson, D E (1998) Dietary acid increases blood and renal cortical acid content in rats. Am J Physiol 274:F97-103
Hayward, A L; Oefner, P J; Sabatini, S et al. (1998) Modeling and analysis of competitive RT-PCR. Nucleic Acids Res 26:2511-8
Wesson, D E; Simoni, J; Green, D F (1998) Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells. J Clin Invest 101:578-83
Wesson, D E; Dolson, G M (1997) Endothelin-1 increases rat distal tubule acidification in vivo. Am J Physiol 273:F586-94
Wesson, D E (1997) Endogenous endothelins mediate increased distal tubule acidification induced by dietary acid in rats. J Clin Invest 99:2203-11

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