Studies of Intracellular Cholesterol Metablolism

Liscum, Laura

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 3R01DK036505-06S1
• Application #: 3234939
• Study Section: Metabolism Study Section (MET)
• Project Start: 1990-01-10
• Project End: 1993-12-31
• Budget Start: 1992-06-01
• Budget End: 1993-12-31
• Support Year: 6
• Fiscal Year: 1992

Institution

• Name: Tufts University
• Type: Schools of Medicine
• DUNS #: 604483045
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02111

Publications

Underwood, K W; Andemariam, B; McWilliams, G L et al. (1996) Quantitative analysis of hydrophobic amine inhibition of intracellular cholesterol transport. J Lipid Res 37:1556-68

Natowicz, M R; Stoler, J M; Prence, E M et al. (1995) Marked heterogeneity in Niemann-Pick disease, type C. Clinical and ultrastructural findings. Clin Pediatr (Phila) 34:190-7

Liscum, L; Dahl, N K (1992) Intracellular cholesterol transport. J Lipid Res 33:1239-54

Liscum, L; Collins, G J (1991) Characterization of Chinese hamster ovary cells that are resistant to 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one inhibition of low density lipoprotein-derived cholesterol metabolism. J Biol Chem 266:16599-606

Liscum, L (1990) Pharmacological inhibition of the intracellular transport of low-density lipoprotein-derived cholesterol in Chinese hamster ovary cells. Biochim Biophys Acta 1045:40-8

Liscum, L; Ruggiero, R M; Faust, J R (1989) The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts. J Cell Biol 108:1625-36

Liscum, L; Faust, J R (1989) The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one. J Biol Chem 264:11796-806