Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK037050-11
Application #
2139952
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1989-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Jacobson, E D; Bunnett, N W (1997) G protein-coupled receptor signaling: implications for the digestive system. Dig Dis 15:207-42
Brooks, E C; Mahr, N N; Radisavljevic, Z et al. (1997) Nitric oxide attenuates and xanthine oxidase exaggerates lung damage-induced gut injury. Am J Physiol 272:G845-52
Terada, L S; Radisavljevic, Z; Mahr, N N et al. (1997) Xanthine oxidase decreases production of gut wall nitric oxide. Proc Soc Exp Biol Med 216:410-3
Terada, L S; Mahr, N N; Jacobson, E D (1996) Nitric oxide decreases lung injury after intestinal ischemia. J Appl Physiol 81:2456-60
Levine, J S; Jacobson, E D (1995) Intestinal ischemic disorders. Dig Dis 13:3-24
Pawlik, W W; Gustaw, P; Jacobson, E D et al. (1995) Nitric oxide mediates intestinal hyperaemic responses to intraluminal bile-oleate. Pflugers Arch 429:301-5
Remak, G; Hottenstein, O D; Jacobson, E D (1994) Multifactorial mediation of post norepinephrine induced intestinal hyperemia. J Physiol Pharmacol 45:241-57
Remak, G; Hottenstein, O D; Jacobson, E D (1994) Adrenergic, purinergic, and endothelial mediators and modulators of norepinephrine-induced mesenteric autoregulatory escape. Dig Dis Sci 39:1655-64
Jacobson, E D; Pawlik, W W (1994) Adenosine regulation of mesenteric vasodilation. Gastroenterology 107:1168-80
Berguer, R; Hottenstein, O D; Palen, T E et al. (1993) Bradykinin-induced mesenteric vasodilation is mediated by B2-subtype receptors and nitric oxide. Am J Physiol 264:G492-6

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