Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK038130-02S1
Application #
3237337
Study Section
Molecular Biology Study Section (MBY)
Project Start
1986-04-01
Project End
1988-03-31
Budget Start
1988-01-01
Budget End
1988-03-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Sone, T; Kerner, S; Pike, J W (1991) Vitamin D receptor interaction with specific DNA. Association as a 1,25-dihydroxyvitamin D3-modulated heterodimer. J Biol Chem 266:23296-305
Sone, T; Ozono, K; Pike, J W (1991) A 55-kilodalton accessory factor facilitates vitamin D receptor DNA binding. Mol Endocrinol 5:1578-86
Pike, J W (1991) Vitamin D3 receptors: structure and function in transcription. Annu Rev Nutr 11:189-216
Ozono, K; Sone, T; Pike, J W (1991) The genomic mechanism of action of 1,25-dihydroxyvitamin D3. J Bone Miner Res 6:1021-7
Ozono, K; Liao, J; Kerner, S A et al. (1990) The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer. J Biol Chem 265:21881-8
Liao, J; Ozono, K; Sone, T et al. (1990) Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A 87:9751-5
McDonnell, D P; Scott, R A; Kerner, S A et al. (1989) Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Mol Endocrinol 3:635-44
Kerner, S A; Scott, R A; Pike, J W (1989) Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3. Proc Natl Acad Sci U S A 86:4455-9
Allegretto, E A; Pike, J W; Haussler, M R (1987) Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species. J Biol Chem 262:1312-9
Allegretto, E A; Pike, J W; Haussler, M R (1987) C-terminal proteolysis of the avian 1,25-dihydroxyvitamin D3 receptor. Biochem Biophys Res Commun 147:479-85

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