Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK038198-05
Application #
2140316
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1987-01-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Surgery
Type
Schools of Medicine
DUNS #
129348186
City
Hershey
State
PA
Country
United States
Zip Code
17033
Xing, L; Karinch, A M; Kauffman Jr, G L (1998) Mesolimbic expression of neurotensin and neurotensin receptor during stress-induced gastric mucosal injury. Am J Physiol 274:R38-45
Karinch, A M; Schmidt, G L; Kauffman Jr, G L (1998) Pretreatment with SR48692 has different effects on central neurotensin-induced gastric mucosal defense and inhibition of gastric acid secretion in rats. Brain Res 810:123-9
Barocelli, E; Impicciatore, M; Seaton, J et al. (1991) Localization of central prostaglandin E2 antisecretory effects. Gastroenterology 100:320-7
Xing, L P; Balaban, C; Seaton, J et al. (1991) Mesolimbic dopamine mediates gastric mucosal protection by central neurotensin. Am J Physiol 260:G34-8
Saperas, E; Kauffman, G; Tache, Y (1991) Role of central prostaglandin E2 in the regulation of gastric acid secretion in the rat. Eur J Pharmacol 209:1-7
Gunion, M W; Tache, Y (1990) Brain sites where bombesin and corticotropin-releasing factor influence gastric secretions. Ann N Y Acad Sci 597:92-113
Gunion, M W; Kauffman Jr, G L; Tache, Y (1990) Intrahypothalamic corticotropin-releasing factor elevates gastric bicarbonate and inhibits stress ulcers in rats. Am J Physiol 258:G152-7
Xing, L P; Washington, J; Seaton, J et al. (1990) Monoamine oxidase B inhibition reduces gastric mucosal blood flow, basal acid secretion, and cold water restraint-induced gastric mucosal injury in rats. Dig Dis Sci 35:61-5
Xing, L P; King, J C; Bryan, R M et al. (1990) Effect of neurotensin on regional cerebral glucose utilization in cold water-restrained rats. Am J Physiol 258:G591-5
Zhang, L; Xing, L P; Demers, L et al. (1989) Central neurotensin inhibits gastric acid secretion: an adrenergic mechanism in rats. Gastroenterology 97:1130-4

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