Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK038531-08
Application #
2140575
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1989-06-05
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Pediatrics
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Ramesh, N; Kim, S T; Wei, M Q et al. (1996) High-titer bicistronic retroviral vectors employing foot-and-mouth disease virus internal ribosome entry site. Nucleic Acids Res 24:2697-700
Osborne, W R; Ramesh, N; Lau, S et al. (1995) Gene therapy for long-term expression of erythropoietin in rats. Proc Natl Acad Sci U S A 92:8055-8
Ramesh, N; Shin, Y K; Lau, S et al. (1995) High-level expression from a cytomegalovirus promoter in macrophage cells. Hum Gene Ther 6:1323-7
Clowes, M M; Lynch, C M; Miller, A D et al. (1994) Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes. J Clin Invest 93:644-51
Bauer Jr, T R; Osborne, W R; Kwok, W W et al. (1994) Expression from leukocyte integrin promoters in retroviral vectors. Hum Gene Ther 5:709-16
Geary, R L; Clowes, A W; Lau, S et al. (1994) Gene transfer in baboons using prosthetic vascular grafts seeded with retrovirally transduced smooth muscle cells: a model for local and systemic gene therapy. Hum Gene Ther 5:1211-6
Kuver, R; Ramesh, N; Lau, S et al. (1994) Constitutive mucin secretion linked to CFTR expression. Biochem Biophys Res Commun 203:1457-62
Ramesh, N; Lau, S; Palmer, T D et al. (1993) High-level human adenosine deaminase expression in dog skin fibroblasts is not sustained following transplantation. Hum Gene Ther 4:3-7
Dale, D C; Lau, S; Nash, R et al. (1992) Effect of endotoxin on serum granulocyte and granulocyte-macrophage colony-stimulating factor levels in dogs. J Infect Dis 165:689-94
Lynch, C M; Clowes, M M; Osborne, W R et al. (1992) Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy. Proc Natl Acad Sci U S A 89:1138-42

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