Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK039087-05
Application #
3238783
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1988-12-01
Project End
1994-09-29
Budget Start
1993-12-01
Budget End
1994-09-29
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Whittier Institute for Diabetes & Endoc
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Beattie, G M; Lopez, A D; Otonkoski, T et al. (1999) Transplantation of human fetal pancreas: fresh vs. cultured fetal islets or ICCS. J Mol Med 77:70-3
Cirulli, V; Crisa, L; Beattie, G M et al. (1998) KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development. J Cell Biol 140:1519-34
Wang, S; Beattie, G M; Mally, M I et al. (1997) Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas. Cell Transplant 6:59-67
Wang, S; Beattie, G M; Hayek, A et al. (1996) Development of a VSV-G protein pseudotyped retroviral vector system expressing dominant oncogenes from a lacO-modified inducible LTR promoter. Gene 182:145-50
Beattie, G M; Rubin, J S; Mally, M I et al. (1996) Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact. Diabetes 45:1223-8
Otonkoski, T; Cirulli, V; Beattie, M et al. (1996) A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth. Endocrinology 137:3131-9
Mally, M I; Cirulli, V; Hayek, A et al. (1996) ICA69 is expressed equally in the human endocrine and exocrine pancreas. Diabetologia 39:474-80
Itkin-Ansari, P; Bain, G; Beattie, G M et al. (1996) E2A gene products are not required for insulin gene expression. Endocrinology 137:3540-3
Mally, M I; Cirulli, V; Otonkoski, T et al. (1996) Ontogeny and tissue distribution of human GAD expression. Diabetes 45:496-501
Otonkoski, T; Hayek, A (1995) Constitution of a biphasic insulin response to glucose in human fetal pancreatic beta-cells with glucagon-like peptide 1. J Clin Endocrinol Metab 80:3779-83

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