Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK039519-08
Application #
2140935
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1988-03-01
Project End
1997-02-28
Budget Start
1995-06-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Summers, S A; Birnbaum, M J (1997) A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake. Biochem Soc Trans 25:981-8
Dudek, H; Datta, S R; Franke, T F et al. (1997) Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-5
Hudson, A W; Birnbaum, M J (1995) Identification of a nonneuronal isoform of synaptotagmin. Proc Natl Acad Sci U S A 92:5895-9
Young, A T; Dahl, J; Hausdorff, S F et al. (1995) Phosphatidylinositol 3-kinase binding to polyoma virus middle tumor antigen mediates elevation of glucose transport by increasing translocation of the GLUT1 transporter. Proc Natl Acad Sci U S A 92:11613-7
Yeh, J I; Gulve, E A; Rameh, L et al. (1995) The effects of wortmannin on rat skeletal muscle. Dissociation of signaling pathways for insulin- and contraction-activated hexose transport. J Biol Chem 270:2107-11
Verhey, K J; Yeh, J I; Birnbaum, M J (1995) Distinct signals in the GLUT4 glucose transporter for internalization and for targeting to an insulin-responsive compartment. J Cell Biol 130:1071-9
Hausdorff, S F; Bennett, A M; Neel, B G et al. (1995) Different signaling roles of SHPTP2 in insulin-induced GLUT1 expression and GLUT4 translocation. J Biol Chem 270:12965-8
Yeh, J I; Verhey, K J; Birnbaum, M J (1995) Kinetic analysis of glucose transporter trafficking in fibroblasts and adipocytes. Biochemistry 34:15523-31
Hausdorff, S F; Frangioni, J V; Birnbaum, M J (1994) Role of p21ras in insulin-stimulated glucose transport in 3T3-L1 adipocytes. J Biol Chem 269:21391-4
Fingar, D C; Birnbaum, M J (1994) A role for Raf-1 in the divergent signaling pathways mediating insulin-stimulated glucose transport. J Biol Chem 269:10127-32

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