Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK040330-08
Application #
2141287
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1988-09-01
Project End
1998-04-30
Budget Start
1995-05-01
Budget End
1998-04-30
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Klarlund, J K; Rameh, L E; Cantley, L C et al. (1998) Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:1859-62
Shpetner, H; Joly, M; Hartley, D et al. (1996) Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J Cell Biol 132:595-605
Hartley, D; Corvera, S (1996) Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism. J Biol Chem 271:21939-43
Joly, M; Kazlauskas, A; Corvera, S (1995) Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J Biol Chem 270:13225-30
Hartley, D; Meisner, H; Corvera, S (1995) Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. J Biol Chem 270:18260-3
Joly, M; Kazlauskas, A; Fay, F S et al. (1994) Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science 263:684-7
Chakrabarti, R; Joly, M; Corvera, S (1993) Redistribution of clathrin-coated vesicle adaptor complexes during adipocytic differentiation of 3T3-L1 cells. J Cell Biol 123:79-87
Kapeller, R; Chakrabarti, R; Cantley, L et al. (1993) Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton. Mol Cell Biol 13:6052-63
Corvera, S; Jaspers, S; Pasceri, M (1991) Acute inhibition of insulin-stimulated glucose transport by the phosphatase inhibitor, okadaic acid. J Biol Chem 266:9271-5
Corvera, S; Capocasale, R J (1990) Enhanced phosphorylation of a coated vesicle polypeptide in response to insulin stimulation of rat adipocytes. J Biol Chem 265:15963-9

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