Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK040456-02
Application #
3240736
Study Section
Metabolism Study Section (MET)
Project Start
1989-05-01
Project End
1992-04-30
Budget Start
1990-05-01
Budget End
1991-04-30
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Xu, Jie; Messina, Joseph L (2009) Crosstalk between growth hormone and insulin signaling. Vitam Horm 80:125-53
Bennett, William L; Ji, Shaonin; Messina, Joseph L (2007) Insulin regulation of growth hormone receptor gene expression. Evidence for a transcriptional mechanism of down-regulation in rat hepatoma cells. Mol Cell Endocrinol 274:53-9
Bennett, William L; Keeton, Adam B; Ji, Shaonin et al. (2007) Insulin regulation of growth hormone receptor gene expression: involvement of both the PI-3 kinase and MEK/ERK signaling pathways. Endocrine 32:219-26
Xu, Jie; Liu, Zhongyu; Clemens, Thomas L et al. (2006) Insulin reverses growth hormone-induced homologous desensitization. J Biol Chem 281:21594-606
Xu, Jie; Keeton, Adam B; Franklin, John L et al. (2006) Insulin enhances growth hormone induction of the MEK/ERK signaling pathway. J Biol Chem 281:982-92
Schwacha, Martin G; Holland, Lawanda T; Chaudry, Irshad H et al. (2005) Genetic variability in the immune-inflammatory response after major burn injury. Shock 23:123-8
Xu, Jie; Ji, Shaonin; Venable, Derwei Y et al. (2005) Prolonged insulin treatment inhibits GH signaling via STAT3 and STAT1. J Endocrinol 184:481-92
Xu, Jie; Keeton, Adam B; Wu, Liyu et al. (2005) Gene 33 inhibits apoptosis of breast cancer cells and increases poly(ADP-ribose) polymerase expression. Breast Cancer Res Treat 91:207-15
Keeton, Adam B; Bortoff, Katherine D; Franklin, J Lee et al. (2005) Blockade of rapid versus prolonged extracellularly regulated kinase 1/2 activation has differential effects on insulin-induced gene expression. Endocrinology 146:2716-25
Keeton, Adam B; Messina, Joseph L (2005) Modulation of Elk-dependent-transcription by Gene33. J Cell Biochem 94:1190-8

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