Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK041215-03S1
Application #
3241839
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1989-05-01
Project End
1993-04-30
Budget Start
1991-05-01
Budget End
1993-04-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Type
Schools of Veterinary Medicine
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
March, T H; Jeffery, E H; Wallig, M A (1998) The cruciferous nitrile, crambene, induces rat hepatic and pancreatic glutathione S-transferases. Toxicol Sci 42:82-90
Davis, M A; Wallig, M A; Eaton, D et al. (1993) Differential effect of cyanohydroxybutene on glutathione synthesis in liver and pancreas of male rats. Toxicol Appl Pharmacol 123:257-64
Davis, M A; Wallig, M A; Jeffery, E H (1993) In vitro metabolism of cyanohydroxybutene: formation of a glutathione-S-transferase catalyzed product. Res Commun Chem Pathol Pharmacol 79:343-53
Wallig, M A; Kuchan, M J; Milner, J A (1993) Differential effects of cyanohydroxybutene and selenium on normal and neoplastic canine mammary cells in vitro. Toxicol Lett 69:97-105
Wallig, M A; Kore, A M; Crawshaw, J et al. (1992) Separation of the toxic and glutathione-enhancing effects of the naturally occurring nitrile, cyanohydroxybutene. Fundam Appl Toxicol 19:598-606
Wallig, M A; Jeffery, E H (1990) Enhancement of pancreatic and hepatic glutathione levels in rats during cyanohydroxybutene intoxication. Fundam Appl Toxicol 14:144-59