Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK041480-03
Application #
3242235
Study Section
General Medicine B Study Section (GMB)
Project Start
1989-06-01
Project End
1994-05-31
Budget Start
1990-09-01
Budget End
1991-05-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Type
Schools of Medicine
DUNS #
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Ueda, N; Kaushal, G P; Hong, X et al. (1998) Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Kidney Int 54:399-406
Hagar, H; Ueda, N; Shah, S V (1997) Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells. Kidney Int 51:1747-53
Ueda, N; Walker, P D; Hsu, S M et al. (1995) Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc Natl Acad Sci U S A 92:7202-6
Ueda, N; Guidet, B; Shah, S V (1994) Measurement of intracellular generation of hydrogen peroxide by rat glomeruli in vitro. Kidney Int 45:788-93
Kaushal, G P; Walker, P D; Shah, S V (1994) An old enzyme with a new function: purification and characterization of a distinct matrix-degrading metalloproteinase in rat kidney cortex and its identification as meprin. J Cell Biol 126:1319-27
Golconda, M S; Ueda, N; Shah, S V (1993) Evidence suggesting that iron and calcium are interrelated in oxidant-induced DNA damage. Kidney Int 44:1228-34
Ueda, N; Guidet, B; Shah, S V (1993) Gentamicin-induced mobilization of iron from renal cortical mitochondria. Am J Physiol 265:F435-9
Mayeux, P R; Shah, S V (1993) Glomerular thromboxane A2/prostaglandin H2 receptors: characterization and effect of adriamycin-induced nephrotic syndrome. Biochim Biophys Acta 1181:148-54
Ueda, N; Shah, S V (1992) Endonuclease-induced DNA damage and cell death in oxidant injury to renal tubular epithelial cells. J Clin Invest 90:2593-7
Baliga, R; Baliga, M; Shah, S V (1992) Effect of selenium-deficient diet in experimental glomerular disease. Am J Physiol 263:F56-61

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