Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK042159-05
Application #
2142139
Study Section
Pathology A Study Section (PTHA)
Project Start
1990-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Hunley, T E; Kon, V (2001) Update on endothelins - biology and clinical implications. Pediatr Nephrol 16:752-62
Hunley, T E; Tamura, M; Stoneking, B J et al. (2000) The angiotensin type II receptor tonically inhibits angiotensin- converting enzyme in AT2 null mutant mice. Kidney Int 57:570-7
Hohenfellner, K; Hunley, T E; Yerkes, E et al. (1999) Angiotensin II, type 2 receptor in the development of vesico-ureteric reflux. BJU Int 83:318-22
Hohenfellner, K; Hunley, T E; Schloemer, C et al. (1999) Angiotensin type 2 receptor is important in the normal development of the ureter. Pediatr Nephrol 13:187-91
Gainer, J V; Hunley, T E; Kon, V et al. (1997) Angiotensin II type I receptor polymorphism in African Americans lower frequency of the C1166 variant. Biochem Mol Biol Int 43:227-31
Hunley, T E; Julian, B A; Phillips 3rd, J A et al. (1996) Angiotensin converting enzyme gene polymorphism: potential silencer motif and impact on progression in IgA nephropathy. Kidney Int 49:571-7
Fogo, A; Kon, V (1996) Treatment of hypertension. Semin Nephrol 16:555-66
Iwasaki, S; Homma, T; Matsuda, Y et al. (1995) Endothelin receptor subtype B mediates autoinduction of endothelin-1 in rat mesangial cells. J Biol Chem 270:6997-7003
Kon, V; Hunley, T E; Fogo, A (1995) Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Studies in chronic cyclosporine nephrotoxicity in rats. Transplantation 60:89-95
Hunley, T E; Iwasaki, S; Homma, T et al. (1995) Nitric oxide and endothelin in pathophysiological settings. Pediatr Nephrol 9:235-44

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