Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK042193-03S1
Application #
3243253
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1990-01-01
Project End
1993-03-31
Budget Start
1992-01-01
Budget End
1993-03-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Grossman, M; Raper, S E; Kozarsky, K et al. (1994) Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia. Nat Genet 6:335-41
Wu, G Y; Wilson, J M; Shalaby, F et al. (1991) Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J Biol Chem 266:14338-42
Chowdhury, J R; Grossman, M; Gupta, S et al. (1991) Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits. Science 254:1802-5
Wilson, J M; Chowdhury, N R; Grossman, M et al. (1990) Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. Proc Natl Acad Sci U S A 87:8437-41