Peraldi, P; Xu, M; Spiegelman, B M (1997) Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling. J Clin Invest 100:1863-9
|
Hotamisligil, G S; Arner, P; Atkinson, R L et al. (1997) Differential regulation of the p80 tumor necrosis factor receptor in human obesity and insulin resistance. Diabetes 46:451-5
|
Hu, E; Liang, P; Spiegelman, B M (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271:10697-703
|
Hotamisligil, G S; Peraldi, P; Budavari, A et al. (1996) IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:665-8
|
Hotamisligil, G S; Arner, P; Caro, J F et al. (1995) Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95:2409-15
|
Hotamisligil, G S; Murray, D L; Choy, L N et al. (1994) Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 91:4854-8
|
Hotamisligil, G S; Budavari, A; Murray, D et al. (1994) Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J Clin Invest 94:1543-9
|
Platt, K A; Claffey, K P; Wilkison, W O et al. (1994) Independent regulation of adipose tissue-specificity and obesity response of the adipsin promoter in transgenic mice. J Biol Chem 269:28558-62
|
Hotamisligil, G S; Shargill, N S; Spiegelman, B M (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87-91
|
White, R T; Damm, D; Hancock, N et al. (1992) Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem 267:9210-3
|