Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK042543-05
Application #
2142362
Study Section
General Medicine B Study Section (GMB)
Project Start
1991-02-01
Project End
1997-06-30
Budget Start
1995-02-10
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Kinane, T B; Komatsuzaki, K; Aleixo, M D et al. (1999) Regulation of the G protein Galphai2 by growth and development in fetal airway epithelium. Am J Respir Cell Mol Biol 20:35-42
Kinane, T B; Kang, I; Chu, A et al. (1997) G alpha(i-2) mediates renal LLC-PK1 growth by a Raf-independent activation of p42/p44 MAP kinase. Am J Physiol 272:F273-82
Kinane, T B; Finder, J D; Kawashima, A et al. (1995) LLC-PK1 cell growth is repressed by WT1 inhibition of G-protein alpha i-2 protooncogene transcription. J Biol Chem 270:30760-4
de Almeida, J B; Holtzman, E J; Peters, P et al. (1994) Targeting of chimeric G alpha i proteins to specific membrane domains. J Cell Sci 107 ( Pt 3):507-15
Kinane, T B; Finder, J D; Kawashima, A et al. (1994) Growth of LLC-PK1 renal cells is mediated by EGR-1 up-regulation of G protein alpha i-2 protooncogene transcription. J Biol Chem 269:27503-9
Holtzman, E J; Kinane, T B; West, K et al. (1993) Transcriptional regulation of G-protein alpha i subunit genes in LLC-PK1 renal cells and characterization of the porcine G alpha 1-3 gene promoter. J Biol Chem 268:3964-75
Kinane, T B; Shang, C; Finder, J D et al. (1993) cAMP regulates G-protein alpha i-2 subunit gene transcription in polarized LLC-PK1 cells by induction of a CCAAT box nuclear binding factor. J Biol Chem 268:24669-76