Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK042879-05S1
Application #
2142608
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1990-07-01
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Wu, K D; Bungard, D; Lytton, J (2001) Regulation of SERCA Ca2+ pump expression by cytoplasmic Ca2+ in vascular smooth muscle cells. Am J Physiol Cell Physiol 280:C843-51
Horiguchi, M; Kimura, M; Lytton, J et al. (1999) The relationship between Ca2+-ATPase and freely exchangeable Ca2+ in the dense tubules: a study in platelets from women. Am J Hypertens 12:120-7
Poch, E; Leach, S; Snape, S et al. (1998) Functional characterization of alternatively spliced human SERCA3 transcripts. Am J Physiol 275:C1449-58
Horiguchi, M; Kimura, M; Lytton, J et al. (1998) Ca2+ in the dense tubules: a model of platelet Ca2+ load. Hypertension 31:595-602
Yu, A S; Boim, M; Hebert, S C et al. (1995) Molecular characterization of renal calcium channel beta-subunit transcripts. Am J Physiol 268:F525-31
Krieger, J A; Davila, D R; Lytton, J et al. (1995) Inhibition of sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCA) by polycyclic aromatic hydrocarbons in HPB-ALL human T cells and other tissues. Toxicol Appl Pharmacol 133:102-8
Wu, K D; Lee, W S; Wey, J et al. (1995) Localization and quantification of endoplasmic reticulum Ca(2+)-ATPase isoform transcripts. Am J Physiol 269:C775-84
Wu, K D; Lytton, J (1993) Molecular cloning and quantification of sarcoplasmic reticulum Ca(2+)-ATPase isoforms in rat muscles. Am J Physiol 264:C333-41
Toyofuku, T; Kurzydlowski, K; Lytton, J et al. (1992) The nucleotide binding/hinge domain plays a crucial role in determining isoform-specific Ca2+ dependence of organellar Ca(2+)-ATPases. J Biol Chem 267:14490-6
Yu, A S; Hebert, S C; Brenner, B M et al. (1992) Molecular characterization and nephron distribution of a family of transcripts encoding the pore-forming subunit of Ca2+ channels in the kidney. Proc Natl Acad Sci U S A 89:10494-8

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