Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043142-07
Application #
2142803
Study Section
Endocrinology Study Section (END)
Project Start
1990-08-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Moncur, J T; Park, J P; Memoli, V A et al. (1998) The ""Spot 14"" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism. Proc Natl Acad Sci U S A 95:6989-94
Cunningham, B A; Moncur, J T; Huntington, J T et al. (1998) ""Spot 14"" protein: a metabolic integrator in normal and neoplastic cells. Thyroid 8:815-25
Brown, S B; Maloney, M; Kinlaw, W B (1997) ""Spot 14"" protein functions at the pretranslational level in the regulation of hepatic metabolism by thyroid hormone and glucose. J Biol Chem 272:2163-6
Moncur, J T; Park, J P; Maloney, M et al. (1997) Assignment of the ""spot 14"" gene (THRSP) to human chromosome band 11q13.5 by in situ hybridization. Cytogenet Cell Genet 78:131-2
Cunningham, B A; Maloney, M; Kinlaw, W B (1997) Spot 14 protein-protein interactions: evidence for both homo- and heterodimer formation in vivo. Endocrinology 138:5184-8
Kinlaw, W B; Church, J L; Harmon, J et al. (1995) Direct evidence for a role of the ""spot 14"" protein in the regulation of lipid synthesis. J Biol Chem 270:16615-8
DePalo, D; Kinlaw, W B; Zhao, C et al. (1994) Effect of selenium deficiency on type I 5'-deiodinase. J Biol Chem 269:16223-8
Kinlaw, W B; Tron, P; Witters, L A (1993) Thyroid hormone and dietary carbohydrate induce different hepatic zonation of both ""spot 14"" and acetyl-coenzyme-A carboxylase: a novel mechanism of coregulation. Endocrinology 133:645-50