Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043632-05
Application #
2143109
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1990-09-30
Project End
1995-08-31
Budget Start
1994-09-01
Budget End
1995-08-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Hediger, M A; Smith, C P; You, G et al. (1996) Structure, regulation and physiological roles of urea transporters. Kidney Int 49:1615-23
Nussberger, S; Foret, F; Hebert, S C et al. (1996) Nonradioactive monitoring of organic and inorganic solute transport into single Xenopus oocytes by capillary zone electrophoresis. Biophys J 70:998-1005
You, G; Lee, W S; Barros, E J et al. (1995) Molecular characteristics of Na(+)-coupled glucose transporters in adult and embryonic rat kidney. J Biol Chem 270:29365-71
Hediger, M A; Kanai, Y; You, G et al. (1995) Mammalian ion-coupled solute transporters. J Physiol 482:7S-17S
Kanai, Y; Lee, W S; You, G et al. (1994) The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest 93:397-404
Burant, C F; Flink, S; DePaoli, A M et al. (1994) Small intestine hexose transport in experimental diabetes. Increased transporter mRNA and protein expression in enterocytes. J Clin Invest 93:578-85
Hediger, M A; Rhoads, D B (1994) Molecular physiology of sodium-glucose cotransporters. Physiol Rev 74:993-1026
Lee, W S; Kanai, Y; Wells, R G et al. (1994) The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression. J Biol Chem 269:12032-9
Hediger, M A (1994) Structure, function and evolution of solute transporters in prokaryotes and eukaryotes. J Exp Biol 196:15-49
Wells, R G; Mohandas, T K; Hediger, M A (1993) Localization of the Na+/glucose cotransporter gene SGLT2 to human chromosome 16 close to the centromere. Genomics 17:787-9

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