Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK043690-02S1
Application #
3245098
Study Section
General Medicine B Study Section (GMB)
Project Start
1992-02-01
Project End
1996-01-31
Budget Start
1993-12-01
Budget End
1994-01-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Chen, T C; Holick, M F (2000) Hexafluoro-1,25-dihydroxyvitamin D3 has markedly increased potency in inhibiting proliferation of cultured human keratinocytes compared with 1,25-dihydroxyvitamin D3. Br J Dermatol 143:72-8
Chen, T C; Persons, K S; Lu, Z et al. (2000) An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3. J Nutr Biochem 11:267-72
Schilli, M B; Ray, S; Paus, R et al. (1997) Control of hair growth with parathyroid hormone (7-34). J Invest Dermatol 108:928-32
Holick, M F; Chen, M L; Kong, X F et al. (1996) Clinical uses for calciotropic hormones 1,25-dihydroxyvitamin D3 and parathyroid hormone-related peptide in dermatology: a new perspective. J Investig Dermatol Symp Proc 1:1-9
Chen, M L; Perez, A; Sanan, D K et al. (1996) Induction of vitamin D receptor mRNA expression in psoriatic plaques correlates with clinical response to 1,25-dihydroxyvitamin D3. J Invest Dermatol 106:637-41
Perez, A; Raab, R; Chen, T C et al. (1996) Safety and efficacy of oral calcitriol (1,25-dihydroxyvitamin D3) for the treatment of psoriasis. Br J Dermatol 134:1070-8
Perez, A; Chen, T C; Turner, A et al. (1996) Efficacy and safety of topical calcitriol (1,25-dihydroxyvitamin d3) for the treatment of psoriasis. Br J Dermatol 134:238-46
Ray, S; Ray, R; Holick, M F (1995) Metabolism of 3H-1 alpha,25-dihydroxyvitamin D3 in cultured human keratinocytes. J Cell Biochem 59:117-22
Perez, A; Chen, T C; Turner, A et al. (1995) Pilot study of topical calcitriol (1,25-dihydroxyvitamin D3) for treating psoriasis in children. Arch Dermatol 131:961-2
Hanafin, N M; Chen, T C; Heinrich, G et al. (1995) Cultured human fibroblasts and not cultured human keratinocytes express a PTH/PTHrP receptor mRNA. J Invest Dermatol 105:133-7

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