Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK044155-07S1
Application #
2597776
Study Section
Special Emphasis Panel (ZRG2-REN (02))
Project Start
1991-07-01
Project End
2000-06-30
Budget Start
1997-07-01
Budget End
1998-06-30
Support Year
7
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Xu, Bin; Yang, Wei-Hsiung; Gerin, Isabelle et al. (2009) Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis. Mol Cell Biol 29:1719-34
Diallo, Ericka M; Wilhelm Jr, Kenneth G; Thompson, Deborah L et al. (2007) Variable RXR requirements for thyroid hormone responsiveness of endogenous genes. Mol Cell Endocrinol 264:149-56
Yu, Jingcheng; Koenig, Ronald J (2006) Induction of type 1 iodothyronine deiodinase to prevent the nonthyroidal illness syndrome in mice. Endocrinology 147:3580-5
Au, Amy Y M; McBride, Claire; Wilhelm Jr, Kenneth G et al. (2006) PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth. Endocrinology 147:367-76
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Xu, Bin; Koenig, Ronald J (2005) Regulation of thyroid hormone receptor alpha2 RNA binding and subcellular localization by phosphorylation. Mol Cell Endocrinol 245:147-57
Diallo, Ericka M; Thompson, Deborah L; Koenig, Ronald J (2005) A method for efficient production of recombinant thyroid hormone receptors reveals that receptor homodimer-DNA binding is enhanced by the coactivator TIF2. Protein Expr Purif 40:292-8
Xu, Bin; Koenig, Ronald J (2004) An RNA-binding domain in the thyroid hormone receptor enhances transcriptional activation. J Biol Chem 279:33051-6
Wu, Y; Xu, B; Koenig, R J (2001) Thyroid hormone response element sequence and the recruitment of retinoid X receptors for thyroid hormone responsiveness. J Biol Chem 276:3929-36
Yu, J; Koenig, R J (2000) Regulation of hepatocyte thyroxine 5'-deiodinase by T3 and nuclear receptor coactivators as a model of the sick euthyroid syndrome. J Biol Chem 275:38296-301

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