Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044266-04
Application #
2143663
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1992-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Physiology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Brill, S; Zvibel, I; Reid, L M (1999) Expansion conditions for early hepatic progenitor cells from embryonal and neonatal rat livers. Dig Dis Sci 44:364-71
Fiorino, A S; Diehl, A M; Lin, H Z et al. (1998) Maturation-dependent gene expression in a conditionally transformed liver progenitor cell line. In Vitro Cell Dev Biol Anim 34:247-58
Zvibel, I; Fiorino, A S; Brill, S et al. (1998) Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents. Differentiation 63:215-23
Agelli, M; Dello Sbarba, P; Halay, E D et al. (1997) Putative liver progenitor cells: conditions for long-term survival in culture. Histochem J 29:205-17
Reid, L M; Luntz, T L (1997) Ex vivo maintenance of differentiated mammalian cells. Methods Mol Biol 75:31-57
Reid, L M (1996) Stem cell-fed maturational lineages and gradients in signals: relevance to differentiation of epithelia. Mol Biol Rep 23:21-33
Fiorino, A S; Zvibel, I (1996) Disruption of cell-cell adhesion in the presence of sodium butyrate activates expression of the 92 kDa type IV collagenase in MDCK cells. Cell Biol Int 20:489-99
Sigal, S H; Gupta, S; Gebhard Jr, D F et al. (1995) Evidence for a terminal differentiation process in the rat liver. Differentiation 59:35-42
Sigal, S H; Rajvanshi, P; Reid, L M et al. (1995) Demonstration of differentiation in hepatocyte progenitor cells using dipeptidyl peptidase IV deficient mutant rats. Cell Mol Biol Res 41:39-47
Zvibel, I; Brill, S; Reid, L M (1995) Insulin-like growth factor II regulation of gene expression in rat and human hepatomas. J Cell Physiol 162:36-43

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