Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044309-05
Application #
2143698
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1991-08-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Surgery
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Naji, A (1996) Induction of tolerance by intrathymic inoculation of alloantigen. Curr Opin Immunol 8:704-9
Campos, L; Deli, B C; Kern, J H et al. (1995) Survival of MHC deficient mouse heterotopic cardiac allografts and xenografts. Transplant Proc 27:254-5
Campos, L; Naji, A; Deli, B C et al. (1995) Survival of MHC-deficient mouse heterotopic cardiac allografts. Transplantation 59:187-91
Mayo, G L; Posselt, A M; Barker, C F et al. (1994) Prolongation of survival of donor-strain islet xenografts (rat-->mouse) by intrathymic inoculation of xenogeneic islet and bone marrow cells. Transplantation 58:107-9
Markmann, J F; Campos, L; Bhandoola, A et al. (1994) Genetically engineered grafts to study xenoimmunity: a role for indirect antigen presentation in the destruction of major histocompatibility complex antigen deficient xenografts. Surgery 116:242-8;discussion 248-9
Mayo, G L; Posselt, A M; Campos, L et al. (1994) Intrathymic transplantation promotes survival of islet xenografts (rat-->mouse). Transplant Proc 26:758
Campos, L; Posselt, A M; Deli, B C et al. (1994) The failure of intrathymic transplantation of nonimmunogenic islet allografts to promote induction of donor-specific unresponsiveness. Transplantation 57:950-3
Campos, L; Alfrey, E J; Posselt, A M et al. (1993) Intrathymic inoculation of donor cells promotes survival of rat orthotopic liver allografts. Transplant Proc 25:488-9
Odorico, J S; Barker, C F; Markmann, J F et al. (1993) Prolonged survival of rat cardiac allografts after intrathymic inoculation of donor thymocytes. Transplant Proc 25:295-6
Posselt, A M; Barker, C F; Friedman, A L et al. (1993) Intrathymic inoculation of islets at birth prevents autoimmune diabetes and pancreatic insulitis in the BB rat. Transplant Proc 25:301-2

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