Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK044337-04A2S1
Application #
2604997
Study Section
Special Emphasis Panel (ZRG4-GMB (04))
Project Start
1993-01-01
Project End
2001-04-30
Budget Start
1997-07-25
Budget End
1998-04-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Boston University
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Ray, Arjun; Swamy, Narasimha; Ray, Rahul (2008) Cross-talk among structural domains of human DBP upon binding 25-hydroxyvitamin D. Biochem Biophys Res Commun 365:746-50
Swamy, Narasimha; Ray, Rahul (2008) Fatty acid-binding site environments of serum vitamin D-binding protein and albumin are different. Bioorg Chem 36:165-8
Fernandez-Gacio, Ana; Fernandez-Marcos, Carlos; Swamy, Narasimha et al. (2003) Affinity labeling of the nuclear vitamin D receptor with nonsteroidal alkylating agents. Bioorg Med Chem Lett 13:213-6
Kisker, Oliver; Onizuka, Shinya; Becker, Christian M et al. (2003) Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice. Neoplasia 5:32-40
Addo, James K; Swamy, Narasimha; Ray, Rahul (2002) The C(19) position of 25-hydroxyvitamin D(3) faces outward in the vitamin D sterol-binding pocket of vitamin D-binding protein. Bioorg Med Chem Lett 12:279-81
Swamy, Narasimha; Head, James F; Weitz, Daniel et al. (2002) Biochemical and preliminary crystallographic characterization of the vitamin D sterol- and actin-binding by human vitamin D-binding protein. Arch Biochem Biophys 402:14-23
Mohr, S C; Swamy, N; Xu, W et al. (2001) Why do we need a three-dimensional architecture of the ligand-binding domain of the nuclear 1alpha,25-dihydroxyvitamin D(3) receptor? Steroids 66:189-201
Swamy, N; Ghosh, S; Schneider, G B et al. (2001) Baculovirus-expressed vitamin D-binding protein-macrophage activating factor (DBP-maf) activates osteoclasts and binding of 25-hydroxyvitamin D(3) does not influence this activity. J Cell Biochem 81:535-46
Swamy, N; Xu, W; Paz, N et al. (2000) Molecular modeling, affinity labeling, and site-directed mutagenesis define the key points of interaction between the ligand-binding domain of the vitamin D nuclear receptor and 1 alpha,25-dihydroxyvitamin D3. Biochemistry 39:12162-71
Swamy, N; Addo, J; Vskokovic, M R et al. (2000) Probing the vitamin D sterol-binding pocket of human vitamin D-binding protein with bromoacetate affinity labeling reagents containing the affinity probe at C-3, C-6, C-11, and C-19 positions of parent vitamin D sterols. Arch Biochem Biophys 373:471-8

Showing the most recent 10 out of 23 publications