Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK044625-05
Application #
2143936
Study Section
Immunobiology Study Section (IMB)
Project Start
1992-03-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Book McAlexander, M; Yu-Lee, L Y (2001) Sp1 is required for prolactin activation of the interferon regulatory factor-1 gene. Mol Cell Endocrinol 184:135-41
Book McAlexander, M; Yu-Lee, L (2001) Prolactin activation of IRF-1 transcription involves changes in histone acetylation. FEBS Lett 488:91-4
Luo, G; Yu-Lee, L (2000) Stat5b inhibits NFkappaB-mediated signaling. Mol Endocrinol 14:114-23
Herrington, J; Rui, L; Luo, G et al. (1999) A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B. J Biol Chem 274:5138-45
Yu-Lee, L Y; Luo, G; Book, M L et al. (1998) Lactogenic hormone signal transduction. Biol Reprod 58:295-301
Yu-Lee, L; Luo, G; Moutoussamy, S et al. (1998) Prolactin and growth hormone signal transduction in lymphohaemopoietic cells. Cell Mol Life Sci 54:1067-75
Smit, L S; Vanderkuur, J A; Stimage, A et al. (1997) Growth hormone-induced tyrosyl phosphorylation and deoxyribonucleic acid binding activity of Stat5A and Stat5B. Endocrinology 138:3426-34
Wang, Y; O'Neal, K D; Yu-Lee, L (1997) Multiple prolactin (PRL) receptor cytoplasmic residues and Stat1 mediate PRL signaling to the interferon regulatory factor-1 promoter. Mol Endocrinol 11:1353-64
Yu-Lee, L Y (1997) Molecular actions of prolactin in the immune system. Proc Soc Exp Biol Med 215:35-52
Luo, G; Yu-Lee, L (1997) Transcriptional inhibition by Stat5. Differential activities at growth-related versus differentiation-specific promoters. J Biol Chem 272:26841-9

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