Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK044755-02
Application #
3246260
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1992-09-30
Project End
1996-09-29
Budget Start
1993-07-01
Budget End
1993-09-29
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Colorado State University-Fort Collins
Department
Type
Schools of Veterinary Medicine
DUNS #
112617480
City
Fort Collins
State
CO
Country
United States
Zip Code
80523
Miller, D R; Collier, J M; Billings, R E (1997) Protein tyrosine kinase activity regulates nitric oxide synthase induction in rat hepatocytes. Am J Physiol 272:G207-14
Duval, D L; Miller, D R; Collier, J et al. (1996) Characterization of hepatic nitric oxide synthase: identification as the cytokine-inducible form primarily regulated by oxidants. Mol Pharmacol 50:277-84
Carlson, T J; Billings, R E (1996) Role of nitric oxide in the cytokine-mediated regulation of cytochrome P-450. Mol Pharmacol 49:796-801
Duval, D L; Sieg, D J; Billings, R E (1995) Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione. Arch Biochem Biophys 316:699-706
Adamson, G M; Billings, R E (1994) The role of xanthine oxidase in oxidative damage caused by cytokines in cultured mouse hepatocytes. Life Sci 55:1701-9
Adamson, G M; Carlson, T J; Billings, R E (1994) Phospholipase A2 activation in cultured mouse hepatocytes exposed to tumor necrosis factor-alpha. J Biochem Toxicol 9:181-90
Adamson, G M; Billings, R E (1994) Tumor necrosis factor: receptor binding and expression of receptors in cultured mouse hepatocytes. J Pharmacol Exp Ther 269:367-73
Adamson, G M; Billings, R E (1993) Cytokine toxicity and induction of NO synthase activity in cultured mouse hepatocytes. Toxicol Appl Pharmacol 119:100-7