Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045285-04
Application #
2144502
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Linhart, H G; Ishimura-Oka, K; DeMayo, F et al. (2001) C/EBPalpha is required for differentiation of white, but not brown, adipose tissue. Proc Natl Acad Sci U S A 98:12532-7
Timchenko, N A; Wilde, M; Iakova, P et al. (1999) E2F/p107 and E2F/p130 complexes are regulated by C/EBPalpha in 3T3-L1 adipocytes. Nucleic Acids Res 27:3621-30
Burgess-Beusse, B L; Timchenko, N A; Darlington, G J (1999) CCAAT/enhancer binding protein alpha (C/EBPalpha) is an important mediator of mouse C/EBPbeta protein isoform production. Hepatology 29:597-601
Wu, Z; Rosen, E D; Brun, R et al. (1999) Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell 3:151-8
Timchenko, N A; Wilde, M; Kosai, K I et al. (1998) Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteins. Nucleic Acids Res 26:3293-9
Oesterreicher, T J; Leeper, L L; Finegold, M J et al. (1998) Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J 330 ( Pt 3):1165-71
Kimura, T; Christoffels, V M; Chowdhury, S et al. (1998) Hypoglycemia-associated hyperammonemia caused by impaired expression of ornithine cycle enzyme genes in C/EBPalpha knockout mice. J Biol Chem 273:27505-10
Darlington, G J; Ross, S E; MacDougald, O A (1998) The role of C/EBP genes in adipocyte differentiation. J Biol Chem 273:30057-60
Soriano, H E; Kang, D C; Finegold, M J et al. (1998) Lack of C/EBP alpha gene expression results in increased DNA synthesis and an increased frequency of immortalization of freshly isolated mice [correction of rat] hepatocytes. Hepatology 27:392-401
Burgess-Beusse, B L; Darlington, G J (1998) C/EBPalpha is critical for the neonatal acute-phase response to inflammation. Mol Cell Biol 18:7269-77

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