Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045614-03
Application #
2144824
Study Section
General Medicine B Study Section (GMB)
Project Start
1992-09-30
Project End
1996-09-30
Budget Start
1994-09-30
Budget End
1996-09-30
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Kansas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Wallace, D P; Tomich, J M; Eppler, J W et al. (2000) A synthetic channel-forming peptide induces Cl(-) secretion: modulation by Ca(2+)-dependent K(+) channels. Biochim Biophys Acta 1464:69-82
Sullivan, L P; Wallace, D P; Grantham, J J (1998) Epithelial transport in polycystic kidney disease. Physiol Rev 78:1165-91
Tomich, J M; Wallace, D; Henderson, K et al. (1998) Aqueous solubilization of transmembrane peptide sequences with retention of membrane insertion and function. Biophys J 74:256-67
Sullivan, L P; Wallace, D P; Grantham, J J (1998) Chloride and fluid secretion in polycystic kidney disease. J Am Soc Nephrol 9:903-16
Wallace, D P; Tomich, J M; Iwamoto, T et al. (1997) A synthetic peptide derived from glycine-gated Cl- channel induces transepithelial Cl- and fluid secretion. Am J Physiol 272:C1672-9
Grantham, J J (1997) Mechanisms of progression in autosomal dominant polycystic kidney disease. Kidney Int Suppl 63:S93-7
Holleran, A L; Fiskum, G; Kelleher, J K (1997) Quantitative analysis of acetoacetate metabolism in AS-30D hepatoma cells with 13C and 14C isotopic techniques. Am J Physiol 272:E945-51
Grantham, J J; Schreiner, G F; Rome, L et al. (1997) Evidence for inflammatory and secretagogue lipids in cyst fluids from patients with autosomal dominant polycystic kidney disease. Proc Assoc Am Physicians 109:397-408
Sullivan, L P; Grantham, J J (1996) Mechanisms of fluid secretion by polycystic epithelia. Kidney Int 49:1586-91
Wallace, D P; Grantham, J J; Sullivan, L P (1996) Chloride and fluid secretion by cultured human polycystic kidney cells. Kidney Int 50:1327-36

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