Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045659-04
Application #
2144860
Study Section
Biochemical Endocrinology Study Section (BCE)
Program Officer
Linder, Barbara
Project Start
1992-09-30
Project End
1996-09-29
Budget Start
1995-09-30
Budget End
1996-09-29
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
American National Red Cross
Department
Type
DUNS #
003255213
City
Washington
State
DC
Country
United States
Zip Code
20006
Thompson, Brian; Ancellin, Nicolas; Fernandez, Salvador M et al. (2006) Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. Prostaglandins Other Lipid Mediat 80:15-27
Goligorsky, Michael S; Brodsky, Sergey V; Noiri, Eisei (2004) NO bioavailability, endothelial dysfunction, and acute renal failure: new insights into pathophysiology. Semin Nephrol 24:316-23
Ozaki, Harunobu; Hla, Timothy; Lee, Menq-Jer (2003) Sphingosine-1-phosphate signaling in endothelial activation. J Atheroscler Thromb 10:125-31
Ancellin, Nicolas; Colmont, Chantal; Su, Joseph et al. (2002) Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. J Biol Chem 277:6667-75
Lee, M J; Thangada, S; Paik, J H et al. (2001) Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol Cell 8:693-704
Paik, J H; Chae Ss; Lee, M J et al. (2001) Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. J Biol Chem 276:11830-7
Hla, T (2001) Sphingosine 1-phosphate receptors. Prostaglandins Other Lipid Mediat 64:135-42
Kluk, M J; Hla, T (2001) Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. Circ Res 89:496-502
Hla, T; Lee, M J; Ancellin, N et al. (2001) Lysophospholipids--receptor revelations. Science 294:1875-8
Morales-Ruiz, M; Lee, M J; Zollner, S et al. (2001) Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J Biol Chem 276:19672-7

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