Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK045741-03
Application #
2016591
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1994-09-30
Project End
1998-03-31
Budget Start
1996-09-16
Budget End
1998-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Vemulakonda, Vijaya M; Somogyi, George T; Kiss, Susanna et al. (2005) Inhibitory effect of intravesically applied botulinum toxin A in chronic bladder inflammation. J Urol 173:621-4
Lai, H Henry; Boone, Timothy B; Yang, Guang et al. (2004) Loss of caveolin-1 expression is associated with disruption of muscarinic cholinergic activities in the urinary bladder. Neurochem Int 45:1185-93
Khera, Mohit; Somogyi, George T; Kiss, Susanna et al. (2004) Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury. Neurochem Int 45:987-93
Szell, Eniko A; Somogyi, George T; de Groat, William C et al. (2003) Developmental changes in spontaneous smooth muscle activity in the neonatal rat urinary bladder. Am J Physiol Regul Integr Comp Physiol 285:R809-16
Somogyi, George T; Zernova, Ganna V; Yoshiyama, Mitsuharu et al. (2003) Change in muscarinic modulation of transmitter release in the rat urinary bladder after spinal cord injury. Neurochem Int 43:73-7
Smith, Christopher P; Boone, Timothy B; de Groat, William C et al. (2003) Effect of stimulation intensity and botulinum toxin isoform on rat bladder strip contractions. Brain Res Bull 61:165-71
Somogyi, George T; Yokoyama, Teruhiko; Szell, Eniko A et al. (2002) Effect of cryoinjury on the contractile parameters of bladder strips: a model of impaired detrusor contractility. Brain Res Bull 59:23-8
Sculptoreanu, A; Yoshimura, N; de Groat, W C et al. (2001) Protein kinase C is involved in M1-muscarinic receptor-mediated facilitation of L-type Ca2+ channels in neurons of the major pelvic ganglion of the adult male rat. Neurochem Res 26:933-42
Yamamoto, T; Ghosh, R; De Groat, W C et al. (2001) Facilitation of transmitter release in the urinary bladders of neonatal and adult rats via alpha1-adrenoceptors. Eur J Pharmacol 414:31-5
Szell, E A; Yamamoto, T; de Groat, W C et al. (2000) Smooth muscle and parasympathetic nerve terminals in the rat urinary bladder have different subtypes of alpha(1) adrenoceptors. Br J Pharmacol 130:1685-91

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