Synthetic Gene Carriers to Treat Cystic Fibrosis

Agency: National Institute of Health (NIH)
Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type: Research Project (R01)
Project #: 5R01DK046052-04
Application #: 2145255
Study Section: Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)


NIH 2001 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco	$222,813
NIH 2000 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco	$216,412
NIH 1999 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco
NIH 1995 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco
NIH 1994 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco
NIH 1993 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco
NIH 1992 R01 DK	Synthetic Gene Carriers to Treat Cystic Fibrosis Szoka, Francis C. / University of California San Francisco

Choi, Joon Sig; MacKay, J Andrew; Szoka Jr, Francis C (2003) Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization. Bioconjug Chem 14:420-9

Sonawane, N D; Szoka Jr, Francis C; Verkman, A S (2003) Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem 278:44826-31

Guo, Xin; Szoka Jr, Francis C (2003) Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Acc Chem Res 36:335-41

Bronich, Tatiana K; Ouyang, Ming; Kabanov, Victor A et al. (2002) Synthesis of vesicles on polymer template. J Am Chem Soc 124:11872-3

Eliaz, R E; Szoka Jr, F C (2002) Robust and prolonged gene expression from injectable polymeric implants. Gene Ther 9:1230-7

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