Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK046607-03
Application #
2145850
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1993-05-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Michigan State University
Department
Physiology
Type
Schools of Arts and Sciences
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Hootman, S R; Jones, J E; Kapoor, R et al. (1998) Sodium, potassium-activated adenosine triphosphatase activity is impaired in the guinea pig pancreatic duct system in streptozotocin-induced diabetes. Biochem Biophys Res Commun 243:869-73
Busik, J V; Hootman, S R; Greenidge, C A et al. (1997) Glucose-specific regulation of aldose reductase in capan-1 human pancreatic duct cells In vitro. J Clin Invest 100:1685-92
de Ondarza, J; Hootman, S R (1997) Confocal microscopic analysis of intracellular pH regulation in isolated guinea pig pancreatic ducts. Am J Physiol 272:G124-34
Hootman, S R; de Ondarza, J (1995) Regulation of goblet cell degranulation in isolated pancreatic ducts. Am J Physiol 268:G24-32
Bhattacharyya, E; Panchal, A; Wilkins, T J et al. (1995) Insulin, transforming growth factors, and substrates modulate growth of guinea pig pancreatic duct cells in vitro. Gastroenterology 109:944-52
de Ondarza, J; Hootman, S R (1995) Regulation of cyclic AMP levels in guinea pig pancreatic ducts and cultured duct epithelial monolayers. Pancreas 11:261-70
Wilkins, T J; de Ondarza, J; Hootman, S R (1994) Intracellular mediators of goblet cell degranulation in isolated pancreatic ducts. Biochem Biophys Res Commun 205:423-8
Hootman, S R; Zukerman, J; Kovalcik, S A (1993) Muscarinic receptors in isolated guinea pig pancreatic ducts. Biochem Pharmacol 46:291-6
Hootman, S R; de Ondarza, J (1993) Overview of pancreatic duct physiology and pathophysiology. Digestion 54:323-30