Role of Mast Cells in Gastric Pathology

Wershil, Barry K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK046819-08
• Application #: 6635006
• Study Section: General Medicine A Subcommittee 2 (GMA)
• Program Officer: Hamilton, Frank A
• Project Start: 1995-09-20
• Project End: 2005-06-30
• Budget Start: 2003-07-01
• Budget End: 2004-06-30
• Support Year: 8
• Fiscal Year: 2003
• Total Cost: $208,794

Institution

• Name: Suny Downstate Medical Center
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 040796328
• City: Brooklyn
• State: NY
• Country: United States
• Zip Code: 11203

Publications

Morganstern, Jeffrey A; Wang, Ming-Yu; Wershil, Barry K (2008) Direct evidence of mast cell participation in acute acid-induced esophageal inflammation in mice. J Pediatr Gastroenterol Nutr 46:134-8

D'Andrea, Michael R; Saban, Marcia R; Gerard, Norma P et al. (2005) Lack of neurokinin-1 receptor expression affects tissue mast cell numbers but not their spatial relationship with nerves. Am J Physiol Regul Integr Comp Physiol 288:R491-500

Saban, Ricardo; Gerard, Norma P; Saban, Marcia R et al. (2002) Mast cells mediate substance P-induced bladder inflammation through an NK(1) receptor-independent mechanism. Am J Physiol Renal Physiol 283:F616-29

Saban, R; Saban, M R; Nguyen, N B et al. (2001) Mast cell regulation of inflammation and gene expression during antigen-induced bladder inflammation in mice. Physiol Genomics 7:35-43

Furuta, G T; Ackerman, S J; Varga, J et al. (2000) Eosinophil granule-derived major basic protein induces IL-8 expression in human intestinal myofibroblasts. Clin Exp Immunol 122:35-40

Schmidt-Choudhury, A; Furuta, G T; Galli, S J et al. (1999) Mast cells contribute to PACAP-induced dermal oedema in mice. Regul Pept 82:65-9

Schmidt-Choudhury, A; Meissner, J; Seebeck, J et al. (1999) Stem cell factor influences neuro-immune interactions: the response of mast cells to pituitary adenylate cyclase activating polypeptide is altered by stem cell factor. Regul Pept 83:73-80

Quackenbush, E J; Wershil, B K; Aguirre, V et al. (1998) Eotaxin modulates myelopoiesis and mast cell development from embryonic hematopoietic progenitors. Blood 92:1887-97

Furuta, G T; Wang, Z S; Wershil, B K (1998) Gastric inflammation during systemic anaphylaxis: neutrophil recruitment in stomach wall of mice does not require mast cell participation. Dig Dis Sci 43:2021-7

Furuta, G T; Ackerman, S J; Lu, L et al. (1998) Stem cell factor influences mast cell mediator release in response to eosinophil-derived granule major basic protein. Blood 92:1055-61