Regulation of Hormone Sensitive Lipase

Kraemer, Fredric B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK046942-02
• Application #: 2146249
• Study Section: Metabolism Study Section (MET)
• Project Start: 1995-01-01
• Project End: 1998-12-31
• Budget Start: 1996-05-18
• Budget End: 1996-12-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Stanford University
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 800771545
• City: Stanford
• State: CA
• Country: United States
• Zip Code: 94305

Publications

Khor, Victor K; Shen, Wen-Jun; Kraemer, Fredric B (2013) Lipid droplet metabolism. Curr Opin Clin Nutr Metab Care 16:632-7

Shen, Wen-Jun; Patel, Shailja; Eriksson, John E et al. (2010) Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis. J Proteome Res 9:1786-94

Shen, Wen-Jun; Patel, Shailja; Miyoshi, Hideaki et al. (2009) Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res 50:2306-13

Shen, Wen-Jun; Patel, Shailja; Yu, Zaixin et al. (2007) Effects of rosiglitazone and high fat diet on lipase/esterase expression in adipose tissue. Biochim Biophys Acta 1771:177-84

Shen, Wen-Jun; Liang, Yu; Wang, Jenny et al. (2007) Regulation of hormone-sensitive lipase in islets. Diabetes Res Clin Pract 75:14-26

Wang, Jining; Shen, Wen-Jun; Patel, Shailja et al. (2005) Mutational analysis of the ""regulatory module"" of hormone-sensitive lipase. Biochemistry 44:1953-9

Smith, Anne J; Sanders, Mark A; Thompson, Brian R et al. (2004) Physical association between the adipocyte fatty acid-binding protein and hormone-sensitive lipase: a fluorescence resonance energy transfer analysis. J Biol Chem 279:52399-405

Kraemer, Fredric B; Shen, Wen-Jun; Harada, Kenji et al. (2004) Hormone-sensitive lipase is required for high-density lipoprotein cholesteryl ester-supported adrenal steroidogenesis. Mol Endocrinol 18:549-57

Shen, Wen-Jun; Patel, Shailja; Natu, Vanita et al. (2003) Interaction of hormone-sensitive lipase with steroidogenic acute regulatory protein: facilitation of cholesterol transfer in adrenal. J Biol Chem 278:43870-6

Ke, Yaohuang; Qiu, Jun; Ogus, Scott et al. (2003) Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Biochem Biophys Res Commun 312:1165-70