Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047003-03
Application #
2146324
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1994-05-10
Project End
1997-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Hess, Karla Ann; Waltz, Susan E; Chan, Edward L et al. (2003) Receptor tyrosine kinase Ron is expressed in mouse reproductive tissues during embryo implantation and is important in trophoblast cell function. Biol Reprod 68:1267-75
Peace, Belinda E; Hill, Kara J; Degen, Sandra J F et al. (2003) Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor. Exp Cell Res 289:317-25
McDowell, Susan A; Mallakin, Ali; Bachurski, Cindy J et al. (2002) The role of the receptor tyrosine kinase Ron in nickel-induced acute lung injury. Am J Respir Cell Mol Biol 26:99-104
Waltz, S E; Eaton, L; Toney-Earley, K et al. (2001) Ron-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses. J Clin Invest 108:567-76
Peace, B E; Hughes, M J; Degen, S J et al. (2001) Point mutations and overexpression of Ron induce transformation, tumor formation, and metastasis. Oncogene 20:6142-51
Muraoka, R S; Waltz, S E; Degen, S J (1999) Expression of hepatocyte growth factor-like protein is repressed by retinoic acid and enhanced by cyclic adenosine 3',5'-monophosphate response element-binding protein (CREB)-binding protein (CBP). Endocrinology 140:187-96
Muraoka, R S; Sun, W Y; Colbert, M C et al. (1999) The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse. J Clin Invest 103:1277-85
Waltz, S E; Toms, C L; McDowell, S A et al. (1998) Characterization of the mouse Ron/Stk receptor tyrosine kinase gene. Oncogene 16:27-42
Degen, S J; McDowell, S A; Waltz, S E et al. (1998) Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein. DNA Seq 8:409-13
Bezerra, J A; Carrick, T L; Degen, J L et al. (1998) Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice. J Clin Invest 101:1175-83

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