Regulation of Glucocorticoid Receptor Gene Expression

Vedeckis, Wayne V.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK047211-03
• Application #: 2146626
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Project Start: 1994-08-01
• Project End: 1998-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Louisiana State University Hsc New Orleans
• Department: Biochemistry
• Type: Schools of Dentistry
• DUNS #: 782627814
• City: New Orleans
• State: LA
• Country: United States
• Zip Code: 70112

Publications

Nunez, B Scott; Geng, Chuan-Dong; Pedersen, Kim Brint et al. (2005) Interaction between the interferon signaling pathway and the human glucocorticoid receptor gene 1A promoter. Endocrinology 146:1449-57

Geng, Chuan-dong; Pedersen, Kim Brint; Nunez, B Scott et al. (2005) Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue- and cell type-specific functions. Biochemistry 44:7395-405

Pedersen, Kim Brint; Geng, Chuan-dong; Vedeckis, Wayne V (2004) Three mechanisms are involved in glucocorticoid receptor autoregulation in a human T-lymphoblast cell line. Biochemistry 43:10851-8

Geng, Chuan-Dong; Vedeckis, Wayne V (2004) Steroid-responsive sequences in the human glucocorticoid receptor gene 1A promoter. Mol Endocrinol 18:912-24

Pedersen, Kim Brint; Vedeckis, Wayne V (2003) Quantification and glucocorticoid regulation of glucocorticoid receptor transcripts in two human leukemic cell lines. Biochemistry 42:10978-90

Nunez, B Scott; Vedeckis, Wayne V (2002) Characterization of promoter 1B in the human glucocorticoid receptor gene. Mol Cell Endocrinol 189:191-9

Breslin, M B; Geng, C D; Vedeckis, W V (2001) Multiple promoters exist in the human GR gene, one of which is activated by glucocorticoids. Mol Endocrinol 15:1381-95

Wagner, B L; Pollio, G; Giangrande, P et al. (1999) The novel progesterone receptor antagonists RTI 3021-012 and RTI 3021-022 exhibit complex glucocorticoid receptor antagonist activities: implications for the development of dissociated antiprogestins. Endocrinology 140:1449-58

Breslin, M B; Vedeckis, W V (1998) The human glucocorticoid receptor promoter upstream sequences contain binding sites for the ubiquitous transcription factor, Yin Yang 1. J Steroid Biochem Mol Biol 67:369-81

Wei, P; Inamdar, N; Vedeckis, W V (1998) Transrepression of c-jun gene expression by the glucocorticoid receptor requires both AP-1 sites in the c-jun promoter. Mol Endocrinol 12:1322-33