Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK047398-01A3
Application #
2146956
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1996-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Pediatrics
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Todisco, A; Ramamoorthy, S; Witham, T et al. (2001) Molecular mechanisms for the antiapoptotic action of gastrin. Am J Physiol Gastrointest Liver Physiol 280:G298-307
Yang, Y K; Dickinson, C; Lai, Y M et al. (2001) Functional properties of an agouti signaling protein variant and characteristics of its cognate radioligand. Am J Physiol Regul Integr Comp Physiol 281:R1877-86
Li, J Y; Finniss, S; Yang, Y K et al. (2000) Agouti-related protein-like immunoreactivity: characterization of release from hypothalamic tissue and presence in serum. Endocrinology 141:1942-50
Yang, Y K; Fong, T M; Dickinson, C J et al. (2000) Molecular determinants of ligand binding to the human melanocortin-4 receptor. Biochemistry 39:14900-11
Sawada, M; Finniss, S; Dickinson, C J (2000) Diminished prohormone convertase 3 expression (PC1/PC3) inhibits progastrin post-translational processing. Regul Pept 89:19-28
Stepan, V M; Sawada, M; Todisco, A et al. (1999) Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells. Mol Med 5:147-59
Stepan, V M; Krametter, D F; Matsushima, M et al. (1999) Glycine-extended gastrin regulates HEK cell growth. Am J Physiol 277:R572-81
Yang, Y K; Dickinson, C J; Zeng, Q et al. (1999) Contribution of melanocortin receptor exoloops to Agouti-related protein binding. J Biol Chem 274:14100-6
Yang, Y K; Thompson, D A; Dickinson, C J et al. (1999) Characterization of Agouti-related protein binding to melanocortin receptors. Mol Endocrinol 13:148-55
Yang, Y k; Dickinson, C; Haskell-Luevano, C et al. (1997) Molecular basis for the interaction of [Nle4,D-Phe7]melanocyte stimulating hormone with the human melanocortin-1 receptor. J Biol Chem 272:23000-10