Identification of Susceptibility Genes for Niddm

Krolewski, Andrzej S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 1R01DK047475-01A2
• Application #: 2147110
• Study Section: Special Emphasis Panel (ZRG4-SOH (03))
• Project Start: 1996-02-27
• Project End: 2001-06-30
• Budget Start: 1996-02-27
• Budget End: 1997-06-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Joslin Diabetes Center
• DUNS #: 071723084
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02215

Publications

Liew, Chong Wee; Bochenski, Jacek; Kawamori, Dan et al. (2010) The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. J Clin Invest 120:2876-88

Keenan, Hillary A; Poznik, G David; Varo, Nerea et al. (2008) Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15. Atherosclerosis 196:863-70

Wanic, K; Malecki, M T; Klupa, T et al. (2007) Lack of association between polymorphisms in the gene encoding protein tyrosine phosphatase 1B (PTPN1) and risk of Type 2 diabetes. Diabet Med 24:650-5

Dunn, J S; Mlynarski, W M; Pezzolesi, M G et al. (2006) Examination of PPP1R3B as a candidate gene for the type 2 diabetes and MODY loci on chromosome 8p23. Ann Hum Genet 70:587-93

Bochenski, Jacek; Placha, Grzegorz; Wanic, Krzysztof et al. (2006) New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals. Diabetes 55:2626-30

Krolewski, A S; Poznik, G D; Placha, G et al. (2006) A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetes. Kidney Int 69:129-36

Malecki, M T; Lebrun, P; Pezzolesi, M et al. (2006) A newly identified mutation in an IPF1 binding site of the insulin gene promoter may predispose to type 2 diabetes mellitus. Diabetologia 49:1985-7

Placha, Grzegorz; Poznik, G David; Dunn, Jonathon et al. (2006) A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes. Diabetes 55:3358-65

Wanic, K; Malecki, M T; Wolkow, P P et al. (2006) Polymorphisms in the gene encoding hepatocyte nuclear factor-4alpha and susceptibility to type 2 diabetes in a Polish population. Diabetes Metab 32:86-8

Kim, Sung-Hoon; Ma, Xiaowei; Weremowicz, Stanislawa et al. (2004) Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23. Diabetes 53:1375-84